Navigating the gloomy sewer system in the Resident Evil 2 remake presents players with several intense survival challenges and valuable hidden resources. One of the most important locked containers in this section is the Treatment Pool Room safe, which holds essential weapon upgrades for both main protagonists. Opening this strongbox gives players a distinct tactical advantage during the difficult encounters later in the game.
Finding the Treatment Pool Room Safe
The Treatment Pool Room is situated within the middle level of the sewer facility. Upon entering from the monitor room area, players can lower a platform bridge to cross over the central gap. The safe sits on a table located on the south side of the room near a blue herb and a lurking zombie threat.
Reaching this area is a mandatory step while progressing through the primary objectives in the sewers. Taking a few extra moments to clear the immediate surroundings ensures you can interact with the safe dial without unexpected interruptions from nearby enemies. It is easily spotted on the table surface next to the southern pathway.
The Exact Treatment Pool Room Safe Combination
Unlocking the Treatment Pool Room safe requires a precise three-step rotation sequence on the mechanical dial. You must turn the dial Left to 2, then Right to 12, and finally Left to 8 before hitting the confirmation key. Following this exact sequence will instantly unlatch the container and grant access to its contents.
This combination remains identical regardless of whether you are playing a standard New Game or a 2nd Run scenario. Furthermore, both characters use the same dial solution, so you can execute the input quickly on subsequent playthroughs. Precision is key, as overshooting any number forces you to restart the sequence from the beginning.
Uncovering the Clue Location
Unlike other safes in Raccoon City that require scouring distant rooms for hidden files, this safe is surprisingly convenient. The developers hid the solution directly on the right side of the safe frame itself, written in faint chalk. Simply panning the camera around the table reveals the numbers immediately without needing extra key items.
This subtle design choice allows observant players to crack the lock right away without back-tracking through dangerous corridors. Inspecting object details closely is a rewarding habit that helps save valuable ammunition and survival resources throughout the campaign.
Weapon Upgrades for Leon and Claire
The items inside the Treatment Pool Room safe vary depending on which character scenario you are actively playing. If you are playing as Leon Kennedy, opening the safe awards the Shotgun Stock for the W-870 shotgun. This custom part dramatically improves the firearm's stability and increases its overall rate of fire.
For players controlling Claire Redfield, the safe yields the Reinforced Frame attachment for the SLS 60 handgun. Equipping this upgrade allows Claire to load heavy-caliber high-powered rounds into her revolver, turning it into a devastating offensive tool. Securing these attachments significantly improves combat performance for the challenging boss fights ahead.
